Acetic Acid → tert-Butyl 4-({[(2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl}amino)piperidine-1-carboxylate

HRID 1153474Notes

Reaction equation

HRID 1153474 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][N:9]1[CH:10]2[CH2:11][CH2:12][CH:13]([C:18](=[O:19])[NH:20][CH:21]3[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]3)[N:14]([C:15]1=[O:16])[CH2:17]2.[CH3:34][C:35](=[O:36])[OH:37].[CH3:38][OH:39]>>[OH:8][N:9]1[CH:10]2[CH2:11][CH2:12][CH:13]([C:18](=[O:19])[NH:20][CH:21]3[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]3)[N:14]([C:15]1=[O:16])[CH2:17]2

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 887MethanolHCID 77568358Tert-butyl 4-[(6-benzyloxy-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carbonyl)amino]piperidine-1-carboxylate

Product 1

HCID 75104689tert-Butyl 4-({[(2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl}amino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-636f194ad2aa446daa58ea67b73d3a73
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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