4-(4-Methylpiperazine-1-carbonyl)phenylboronic acid pinacol ester → 7-[4-(4-Methylpiperazine-1-carbonyl)phenyl]-1-(2,4,5-trifluorobenzyl)-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Reaction equation
[CH3:23][N:24]1[CH2:25][CH2:26][N:27]([C:30](=[O:31])[c:32]2[cH:33][cH:34][c:35]([B:38]3[O:39][C:40]([CH3:41])([CH3:42])[C:43]([CH3:44])([CH3:45])[O:46]3)[cH:36][cH:37]2)[CH2:28][CH2:29]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([n:21][cH:22]1)[NH:6][CH2:7][C:8](=[O:20])[N:9]2[CH2:10][c:11]1[c:12]([F:19])[cH:13][c:14]([F:18])[c:15]([F:17])[cH:16]1>>[c:2]1(-[c:35]2[cH:34][cH:33][c:32]([C:30]([N:27]3[CH2:26][CH2:25][N:24]([CH3:23])[CH2:29][CH2:28]3)=[O:31])[cH:37][cH:36]2)[cH:3][c:4]2[c:5]([n:21][cH:22]1)[NH:6][CH2:7][C:8](=[O:20])[N:9]2[CH2:10][c:11]1[c:12]([F:19])[cH:13][c:14]([F:18])[c:15]([F:17])[cH:16]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c929821319334aa2996f8bab46fa7d0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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