1-Butanol → 1-[4-[2-[4-[Bis(4-fluorophenyl)methyl]-1-piperidinyl]ethoxy]-3-methoxyphenyl]ethanone
Reaction equation
[C:37](=[O:38])([O-:39])[O-:40].[CH2:45]([OH:46])[CH2:47][CH2:48][CH3:49].[CH:50]([Cl:51])([Cl:52])[Cl:53].[Cl:22][CH2:23][CH2:24][O:25][c:26]1[c:27]([O:35][CH3:36])[cH:28][c:29]([C:32]([CH3:33])=[O:34])[cH:30][cH:31]1.[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[c:15]2[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]2)[cH:6][cH:7]1.[I-:44].[K+:41].[K+:42].[K+:43]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]2[CH2:10][CH2:11][N:12]([CH2:23][CH2:24][O:25][c:26]3[c:27]([O:35][CH3:36])[cH:28][c:29]([C:32]([CH3:33])=[O:34])[cH:30][cH:31]3)[CH2:13][CH2:14]2)[c:15]2[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]2)[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-56b967537bd34a0dbd63467f9ac0d0e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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