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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1153761Generated: October 27, 2026

2-Aminoethanimidamide dihydrochloride → 2-Amino-7-(3-phenyl-propyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-d]azepine dihydrochloride

https://huagongshe.com/reaction/1153761

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Aminoethanimidamide dihydrochlorideHCID 18943479—
Reactant1-(3-Phenyl-propyl)-2,3,6,7-tetrahydro-4,5-bis(trimethylsilyloxy)-azepineHCID 20436433—
Product2-Amino-7-(3-phenyl-propyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-d]azepine dihydrochlorideHCID 20436417—

Reaction Steps

This compound was prepared analogous to Example 22 from 1-(3-phenyl-propyl)-2,3,6,7-tetrahydro-4,5-bis(trimethylsilyloxy)-azepine and α-amino-acetamidine dihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04486433
Source datasetuspto-grants-1984_12
ORD IDord-2147ef563cb04eeaa4d432a296a091ae
Source noteuspto-grants-1984_12