2-Aminoethanimidamide dihydrochloride → 6-Ethyl-2-amino-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine

HRID 1153773Notes

Reaction equation

HRID 1153773 reaction equation
[CH2:1]([N:3]1[CH2:7][C:6](O[Si](C)(C)C)=[C:5](O[Si](C)(C)C)[CH2:4]1)[CH3:2].Cl.Cl.[NH2:20][CH2:21][C:22]([NH2:24])=[NH:23]>>[CH2:1]([N:3]1[CH2:7][C:6]2[C:5](=[N:23][C:22]([NH2:24])=[CH:21][N:20]=2)[CH2:4]1)[CH3:2]

Participants

3

Reactant 2

HCID 189434792-Aminoethanimidamide dihydrochlorideHCID 204363871-Ethyl-2,5-dihydro-3,4-bis(trimethylsilyloxy)-pyrrole

Product 1

HCID 204364596-Ethyl-2-amino-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine

Procedure

This compound was prepared analogous to Example 22 from 1-ethyl-2,5-dihydro-3,4-bis(trimethylsilyloxy)-pyrrole and α-amino-acetamidine dihydrochloride.

Sources & evidence

ORD record
ord-da8a17b2b5814231bd33aaf6f5f0dc97
Source dataset
uspto-grants-1984_12
Patent number
US04486433

Reaction notes

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