Iodomethyl pivalate → HCID 131713983, compound

HRID 1153784Notes

Reaction equation

[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:26][O:27][CH2:28][CH3:29])[C:8]([NH:10][CH:11]2[C:24](=[O:25])[N:13]3[C:14]([C:21]([O-:23])=[O:22])=[C:15]([CH2:18][O:19][CH3:20])[CH2:16][S:17][C@H:12]23)=[O:9])[N:6]=1.[Na+].[C:31]([O:37][CH2:38]I)(=[O:36])[C:32]([CH3:35])([CH3:34])[CH3:33]>>[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:26][O:27][CH2:28][CH3:29])[C:8]([NH:10][CH:11]2[C:24](=[O:25])[N:13]3[C:14]([C:21]([O:23][CH2:38][O:37][C:31](=[O:36])[C:32]([CH3:35])([CH3:34])[CH3:33])=[O:22])=[C:15]([CH2:18][O:19][CH3:20])[CH2:16][S:17][C@H:12]23)=[O:9])[N:6]=1

Participants

Reactant 2

HCID 104401Iodomethyl pivalate

HCID 131713984HCID 131713984, compound

Product 1

HCID 131713983HCID 131713983, compound

Procedure

The procedure described in Example 7 was repeated, except that sodium 7-[2-(2-aminothiazol-4-yl)-2-ethoxyiminoacetamido]--3-methoxymethyl-3-cephem-4-carboxylate and iodomethyl pivalate were used, to give the title compound.

Sources & evidence

ORD record: ord-7492e73850324513afab22d6bda8bbaa
Source dataset: uspto-grants-1984_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04486425

Reaction notes

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