Diethyl Ether → HCID 20436919, compound

HRID 1153826Notes

Reaction equation

HRID 1153826 reaction equation
[CH2:1]([N:5]1[C:9](=[O:10])[CH:8]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([O:19]CC)=[O:18])[N:7]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[C:6]1=[O:30])[CH2:2][CH2:3][CH3:4].[OH-].[Na+].CCOCC>C(O)C>[CH2:1]([N:5]1[C:9](=[O:10])[CH:8]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])[N:7]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[C:6]1=[O:30])[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 14798Sodium HydroxideHCID 20340027HCID 20340027, compound

Product 1

HCID 20436919HCID 20436919, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This ester (3.2 g) was dissolved in ethanol (15 ml) and 2N-sodium hydroxide (15 ml) and left at room temperature for 1 hour. The acidic product was isolated by extraction with ether and purified by chromatography on silica gel to give 3-butyl-5-(6-carboxyhexyl)-1-octyl hydantoin as a colourless oil.

Workup

  1. custompurified by chromatography on silica gel

Sources & evidence

ORD record
ord-89894114e5b0427a93ca4ca390fc8fd1
Source dataset
uspto-grants-1984_12
Patent number
US04486443

Reaction notes

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