HCID 13368043, compound → HCID 13368044, compound

Participants

Reaction Steps

A solution of 1.0 g (2 mM) of 9-carbamoyl-9-(2-tert.-butoxycarbonylethyl)fluorene (from Example 6) in 3 ml of trifluoroacetic acid was stirred at 25° C. for four minutes. The reaction mixture was concentrated to dryness by evaporation under reduced pressure to provide an oil. The oil was triturated with diethyl ether and dried to give 670 mg of 9-carbamoyl-9-(2-hydroxycarbonylethyl)fluorene. m.p. 191°-192° C.

Provenance & Evidence