Hydrochloric Acid → 1,5-Dichloro-3,3-dimethylpentan-2-one

Participants

Reaction Conditions

Reaction Steps

A strong stream of hydrogen chloride gas is introduced, from a cylinder, into 476 g (3.25 mols) of 2-chloromethylene-3,3-dimethyltetrahydrofuran, while cooling with ice. The gas is absorbed completely, and the internal temperature increases to 30° C. After complete saturation with hydrogen chloride, the reaction mixture is stirred for a further 2 hours at room temperature. Excess hydrogen chloride is first drawn off by a water pump, and the mixture is then distilled under a good vacuum. 531 g (90% of theory) of 1,5-dichloro-3,3-dimethyl-pentan-2-one of boiling point 85°-90° C./0.3 mbar are obtained. ##STR33##

Provenance & Evidence