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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 11543Generated: October 25, 2026

4-(2-(Pyrrolidin-1-yl)ethoxy)aniline → HCID 178419007, compound

https://huagongshe.com/reaction/11543

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-(Pyrrolidin-1-yl)ethoxy)anilineHCID 6493749—
Reactant5-chloro-3-(hydroxymethylidene)-1H-indol-2-oneHCID 178419036—
ProductHCID 178419007HCID 17841900779%

Reaction Steps

In a manner similar to that described in Example 231, 4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine (632 mg, 1.2 equiv.) and 5-chloro-3-hydroxymethylene-1,3-dihydro-indol-2-one (500 mg, 2.56 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (775 mg, 79%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07098236B2
Source datasetuspto-grants-2006_08
ORD IDord-e4ed8fa2876743748633148fa540b5c2
Source noteuspto-grants-2006_08