HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1154305Generated: November 3, 2026
Water → 5-(Bromomethyl)-1,2-oxazole-3-carboxylic acid
https://huagongshe.com/reaction/1154305
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 5-(Bromomethyl)-3-isoxazolecarbonyl chloride | HCID 13371021 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-(Bromomethyl)-1,2-oxazole-3-carboxylic acid | HCID 13371020 | — |
Reaction Steps
The distilled 5-(bromomethyl)-3-isoxazolecarbonyl chloride (1 g) is dissolved in 2 ml of acetone, cooled to 0° C. and 3 ml of water is added to the solution. The solution is allowed to stand at room temperature for one hour and then the solvent is removed under reduced pressure giving 0.9 g of the acid. It is dried over P2O5 for three days and has mp 143°-148° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04489077 |
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| Source dataset | uspto-grants-1984_12 |
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| ORD ID | ord-1ae08ffe12c64962ad639466b08b91a6 |
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| Source note | uspto-grants-1984_12 |
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