Formic Acid → HCID 20217710, compound

HRID 1154376Notes

Reaction equation

HRID 1154376 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C:10]2[N:11]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:12]3[N:13]([CH2:19][CH2:20][N:21]=3)[C:14](=[O:18])[C:15]=2[N:16]=O)=[CH:4][CH:3]=1.S(S([O-])=O)([O-])=O.[Na+].[Na+].[CH:34](O)=[O:35]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C:10]2[N:11]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:12]3[N:13]([CH2:19][CH2:20][N:21]=3)[C:14](=[O:18])[C:15]=2[NH:16][CH:34]=[O:35])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 284Formic AcidHCID 24489Sodium DithioniteHCID 178448427HCID 178448427, compound

Product 1

HCID 20217710HCID 20217710, compound

Procedure

To a stirred solution of the nitroso compound of Procedure 87 (0.1 mol) in 200 ml. formic acid, sodium dithionite (0.25 mol) is added portionwise. After one hour, the reaction mixture is concentrated in vacuo, the residue dissolved in water and filtered. The filtrate is made basic with concentrated aqueous ammonia, and the product collected.

Workup

  1. concentrationthe reaction mixture is concentrated in vacuo
  2. dissolutionthe residue dissolved in water
  3. filtrationfiltered
  4. customthe product collected

Sources & evidence

ORD record
ord-4d3461e929884dbc9e7dfa33dbb60508
Source dataset
uspto-grants-1984_12
Patent number
US04489078

Reaction notes

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