HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-cyano-2-(hydroxyimino)acetate → 7-AMINO-1-[(4-CHLOROPHENYL)METHYL]-2,3-DIHYDRO-6-NITROSOIMIDAZO-[1,2-a]PYRIMIDIN-5-(1H)-ONE
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-cyano-2-(hydroxyimino)acetate | HCID 6399078 | — |
| Reactant | 1-[(4-Chlorophenyl)methyl]-4,5-dihydro-1H-imidazol-2-amine hydrochloride | HCID 20217712 | — |
| Product | 7-AMINO-1-[(4-CHLOROPHENYL)METHYL]-2,3-DIHYDRO-6-NITROSOIMIDAZO-[1,2-a]PYRIMIDIN-5-(1H)-ONE | HCID 13391420 | — |
Reaction Steps
The product of Procedure 91 was condensed with ethyl oximinocyanoacetate according to the method described in Procedure 1. The crude product, 1.6 g., from 2.9 g. of the product of Procedure 91, was a blue solid, m.p. 273°-275° d, recrystallized from dimethylformamide, m.p. 290°-291° d.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04489078 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-12a122d22e3047fa9138b38c24a72751 |
| Source note | uspto-grants-1984_12 |