Diazomethane → HCID 86737948, compound

HRID 1154396Notes

Reaction equation

HRID 1154396 reaction equation
[Cl:1]/[C:2](/[CH3:9])=[CH:3]\[CH2:4][CH2:5][C:6]([OH:8])=[O:7].[N+](=[CH2:12])=[N-]>CCOCC>[CH3:12][O:7][C:6](=[O:8])[CH2:5][CH2:4]/[CH:3]=[C:2](\[Cl:1])/[CH3:9]

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 20435364HCID 20435364, compound

Product 1

HCID 86737948HCID 86737948, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 10.4 g. of the carboxylic acid prepared according to (c) in 50 ml. of ether was combined with such an amount of ethereal diazomethane solution that there was no longer any liberation of nitrogen during the addition of the reagent and the yellow coloring of the reaction solution remained. Excess diazomethane and solvent were then removed under vacuum, and the residue was distilled with the aid of a water jet aspirator, thus obtaining 10.6 g. of final product, b.p. 87°-89° (18 mm.).

Workup

  1. additionduring the addition of the reagent
  2. customExcess diazomethane and solvent were then removed under vacuum
  3. distillationthe residue was distilled with the aid of a water jet aspirator
  4. customthus obtaining 10.6 g

Sources & evidence

ORD record
ord-61603b3c56644edb996e883fb26e6511
Source dataset
uspto-grants-1984_12
Patent number
US04489092

Reaction notes

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