HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile → HCID 86739807, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile | HCID 9837437 | — |
| Reactant | HCID 86739808 | HCID 86739808 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 86739807 | HCID 86739807 | — |
Reaction Steps
Using the procedure of Example 1, (1R, cis) 2,2-dimethyl-3(Z)-[2-chloro-3-oxo-3-methoxy-propenyl]-cyclopropane-1-carboxylic acid and (S)α-cyano-3-phenoxy-benzyl alcohol were reacted to obtain (S)α-cyano-3-phenoxy-benzyl (1R,cis) 2,2-dimethyl-3(Z)-[2-chloro-3-oxo-3-methoxy-propenyl]-cyclopropane-1-carboxylate with a specific rotation of [α]D20 =+62.5°±1.5° (c=1% in benzene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04489093 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-8aa78ec179684a45b4d8d970f7505615 |
| Source note | uspto-grants-1984_12 |