HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile → HCID 86739822, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile | HCID 9837437 | — |
| Reactant | HCID 86739823 | HCID 86739823 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 86739822 | HCID 86739822 | — |
Reaction Steps
Using the process of Example 1, (1R,cis) 2,2-dimethyl-3(Z)-[2-bromo-3-oxo-3-tert.-butoxy-propenyl]-cyclopropane-1-carboxylic acid and (S)α-cyano-3-phenoxy-benzyl alcohol were reacted to obtain (S)α-cyano-3-phenoxy-benzyl (1R,cis) 2,2-dimethyl-3(Z)-[2-bromo-3-oxo-3-tert.-butoxy-propenyl]-cyclopropane-1-carboxylate with a specific rotation of [α]D20 =+16.5°±2° (c=0.5% in chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04489093 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-fcb66ab7eaed4ba2bf9acc5521e285fa |
| Source note | uspto-grants-1984_12 |