HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile → HCID 13372608, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile | HCID 9837437 | — |
| Reactant | HCID 86739827 | HCID 86739827 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 13372608 | HCID 13372608 | — |
Reaction Steps
(1R,cis,Z) 2,2-dimethyl-3-[2-chloro-3-oxo-3-(1,1-dimethyl-ethoxy)-1-propenyl]-cyclopropane-carboxylic acid prepared as in Step B of Example 34 of European Pat. No. 0050534 and (S)α-cyano-3-phenoxy-benzyl alcohol were reacted to obtain (S)α-cyano-3-phenoxy-benzyl (1R,cis,Z) 2,2-dimethyl-3-[2-chloro-3-oxo-3-(1,1-dimethylethoxy)-1-propenyl]-cyclopropane-carboxylate with a specific rotation of [α]D20 =+15.5°±1.° (c=1% in chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04489093 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-1481a55d0925494cb27038b1c3f63c5a |
| Source note | uspto-grants-1984_12 |