HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile → HCID 13372626, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile | HCID 9837437 | — |
| Reactant | HCID 86739829 | HCID 86739829 | — |
| Product | HCID 13372626 | HCID 13372626 | — |
Reaction Steps
Using the procedure of Step B of Example 43, (1R,cis,Z) 2,2-dimethyl-3-[2-bromo-3-oxo-3-(1-methylpropoxy)-1-propenyl]-cyclopropane carboxylic acid and (S)α-cyano-3-phenoxybenzyl alcohol were reacted to obtain (S)α-cyano-3-phenoxy-benzyl (1R,cis,Z) 2,2-dimethyl-3-[2-bromo-3-oxo-3-(1-methylpropoxy)-1-propenyl]-cyclopropanecarboxylate with a melting point of 76° C. and a specific rotation of [α]D20 =+21.5°±2° (c=0.7% in chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04489093 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-b826714650f24703877eb1864ca83892 |
| Source note | uspto-grants-1984_12 |