HuagongsheHuagongshe Chemistry Print Report · For research reference only
Eclazolast → 5-Chloro-N-(2-ethoxyethyl)-1,3-benzoxazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Eclazolast | HCID 54550 | — |
| Reactant | Ethoxyethylamine | HCID 66970 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Chloro-N-(2-ethoxyethyl)-1,3-benzoxazole-2-carboxamide | HCID 13385553 | 90.3% |
Reaction Steps
A mixture of 2-ethoxyethyl 5-chlorobenzoxazol-2-carboxylate (10 g) and 3.5 g of ethoxyethylamine in 10 ml of THF was stirred at room temperature for 2 hours. The precipitated product was filtered and washed well with hexane to give 9 g of product; mp 110°-111° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04490373 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-e4ad9de29a11461c9ba5b669f4a581a9 |
| Source note | uspto-grants-1984_12 |