反应详情

温度

0 °C

A mixture of 30 ml of acetic anhydride and 8.05 ml (0.1 mole) of pyridine is cooled to 0° C., and 5.4 ml of conc. H2SO4 is added dropwise at 0° C. under stirring. After 10 minutes, the crystals are filtered, washed with diethyl ether and dried under vacuum over P2O5 and KOH. Yield: 18.4 g (84%). IR: 1050 cm-1 sharp band, characteristic for sulfates and sulfate esters. Decomposes above 75° C., very hygroscopic. MW: 219.2 (C7H9O5NS).

1. filtrationthe crystals are filtered
2. washwashed with diethyl ether
3. dry with materialdried under vacuum over P2O5 and KOH
4. customDecomposes above 75° C.