Zincchloride → HCID 86738679, compound

HRID 1154571Notes

Reaction equation

HRID 1154571 reaction equation
[Na].[CH3:2][C:3]1([CH3:18])[CH:12]=[C:11]([O:13][S:14]([CH3:17])(=[O:16])=[O:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[NH:4]1.[Cl-].[Zn+2:20].[Cl-]>CO.O>[Zn:20].[CH3:2][C:3]1([CH3:18])[CH:12]=[C:11]([O:13][S:14]([CH3:17])(=[O:16])=[O:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[NH:4]1

Participants

5

Reactant 2

HCID 3007855ZincchlorideHCID 86738678HCID 86738678, compound

Product 1

HCID 86738679HCID 86738679, compoundYield 87%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

Into a solution of 13.2 g. of (2,2-dimethyl-1,2-dihydroquinoline-4-yl)-methylsulfonic acid sodium salt in 10 ml of methanol 2.7 g or zinc chloride are added. The solution is stirred at room temperature of 2 hours, whereupon it is diluted with 40 ml of water. The solution is then evaporated in vacuo on water bath. 9.9 g (87%) of (2,2-dimethyl-1,2-dihydroquinoline-4-yl)-methylsulfonic acid zinc salt are obtained, melting at 98° to 100° C.

Workup

  1. customThe solution is then evaporated in vacuo on water bath

Sources & evidence

ORD record
ord-fa12594d4eb64327b1ca3496b5149a84
Source dataset
uspto-grants-1984_12
Patent number
US04490394

Reaction notes

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