HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13343677, compound → HCID 13343680, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13343677 | HCID 13343677 | — |
| Reactant | HCID 20434051 | HCID 20434051 | — |
| Product | HCID 13343680 | HCID 13343680 | — |
| Product | HCID 13343681 | HCID 13343681 | — |
Reaction Steps
8-Chloro-5,6-dihydro-3-(o-tolyl)furo[3,2-f]-1,2-benzisoxazole-6-carboxylic acid (4e) was prepared in a fashion analogous to (4a) from (3e). A tenacious impurity resulted in the need for esterification, chromatography, and hydrolysis as with (4d). Trituration in n-hexane produced (4e) in 9.4% yield, m.p. 179°-181° C. Analysis (C17H12ClNO4) C,H,N.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04490384 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-f291ec5900ab4527a48bb26ea90bd829 |
| Source note | uspto-grants-1984_12 |