HCID 20434118, compound → HCID 13365124, compound

Participants

Reaction Steps

A mixture of 1.5 g of α-[(α-methyl-4-methoxyphenethylamino)methyl]-2-benzyloxybenzylalcohol oxalate [the diastereoisomer of M.p. 138°-139° C. (decomp.)], 0.3 g of 10% palladium-carbon and 30 ml of 90% aqueous ethanol is treated in the same manner as described in Example 1-(4-a). The crude product is recrystallized from ethanol in the presence of 300 mg of oxalic acid, and crystalline precipitates are collected by filtration. 0.76 g of α-[(α-methyl-4-methoxyphenethylamino)methyl]-2-hydroxybenzylalcohol 3/2 oxalate [the diastereoisomer of M.p. 175°-176° C. (decomp.)] is thereby obtained.

Provenance & Evidence