HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3,4-Dimethoxyphenyl)acetic acid → (3,4-Dimethoxyphenyl)acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3,4-Dimethoxyphenyl)acetic acid | HCID 7139 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (3,4-Dimethoxyphenyl)acetyl chloride | HCID 3604458 | — |
Reaction Steps
600 ml of thionyl chloride were added dropwise to a suspension of 549.4 gm of 3,4-dimethoxyphenyl-acetic acid in 600 ml of methylene chloride, while stirring, over a period of 2 hours. After the evolution of gas had ceased (16 hours), the mixture was refluxed for an hour. After the volatile components had been removed, the residue was distilled in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04490369 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-0881edcf714d47f2bc25baafd952809c |
| Source note | uspto-grants-1984_12 |