3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → HCID 20433759, compound

HRID 1154650Notes

Reaction equation

HRID 1154650 reaction equation
[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][Cl:15])[CH2:10][CH2:11][C:5]=2[CH:4]=1.[CH3:21][NH:22][CH:23]([CH3:34])[CH2:24][C:25]1[CH:30]=[C:29]([Cl:31])[C:28]([NH2:32])=[C:27]([Cl:33])[CH:26]=1>>[ClH:15].[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][N:22]([CH3:21])[CH:23]([CH3:34])[CH2:24][C:25]3[CH:26]=[C:27]([Cl:33])[C:28]([NH2:32])=[C:29]([Cl:31])[CH:30]=3)[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 130925103-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 20433827HCID 20433827, compound

Product 1

HCID 20433759HCID 20433759, compound

Procedure

This compound was prepared analogous to Example 5(b) from 1-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-3-chloro-propane and N-methyl-N-[2-(4-amino-3,5-dichloro-phenyl)-1-methyl-ethyl]-amine.

Sources & evidence

ORD record
ord-233d062c59d94178a13bdd50d5b1a89d
Source dataset
uspto-grants-1984_12
Patent number
US04490369

Reaction notes

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