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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1154651Generated: November 3, 2026

3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → 1-[7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(2-{4-amino-3-chloro-5-fluorophenyl}-ethyl)-amino]-propane

https://huagongshe.com/reaction/1154651

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 13092510—
ReactantN-methyl-N-[2-(4-amino-3-chloro-5-fluoro-phenyl)-ethyl]-amineHCID 20433831—
Product1-[7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(2-{4-amino-3-chloro-5-fluorophenyl}-ethyl)-amino]-propaneHCID 20433720—

Reaction Steps

This compound was prepared analogous to Example 5(b) from 1-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-3-chloro-propane and N-methyl-N-[2-(4-amino-3-chloro-5-fluoro-phenyl)-ethyl]-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04490369
Source datasetuspto-grants-1984_12
ORD IDord-fe9599ac8ff844d28d260ac55a947ac8
Source noteuspto-grants-1984_12