N-Methylhomoveratrylamine → HCID 13316673, compound

HRID 1154661Notes

Reaction equation

[CH2:1]([O:8][C:9]1[C:24]([OH:25])=[CH:23][C:12]2[CH2:13][C:14](=[O:22])[N:15]([CH2:18][CH2:19][CH2:20]Cl)[CH2:16][CH2:17][C:11]=2[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:26][NH:27][CH2:28][CH2:29][C:30]1[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[C:32]([O:38][CH3:39])[CH:31]=1>>[CH2:1]([O:8][C:9]1[C:24]([OH:25])=[CH:23][C:12]2[CH2:13][C:14](=[O:22])[N:15]([CH2:18][CH2:19][CH2:20][N:27]([CH3:26])[CH2:28][CH2:29][C:30]3[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[C:32]([O:38][CH3:39])[CH:31]=3)[CH2:16][CH2:17][C:11]=2[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 77039N-Methylhomoveratrylamine

HCID 20433765HCID 20433765, compound

Product 1

HCID 13316673HCID 13316673, compound

Procedure

This compound was prepared analogous to Example 5(b) by reacting 1-(7-benzyloxy-8-hydroxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-3-chloro-propane with N-methyl-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-amine.

Workup

customThis compound was prepared analogous to Example 5(b)

Sources & evidence

ORD record: ord-9f1ff050a2954354b89d49e558db0d31
Source dataset: uspto-grants-1984_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04490369

Reaction notes

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