Methanol → HCID 21285245, compound

HRID 1154711Notes

Reaction equation

HRID 1154711 reaction equation
[C:1]([C:3]1[C:4]([N:6]([CH3:11])[C:7](=[O:10])[C:8]=1Cl)=[O:5])#[N:2].[CH3:12][OH:13]>>[C:1]([C:3]1[C:4]([N:6]([CH3:11])[C:7](=[O:10])[C:8]=1[O:13][CH3:12])=[O:5])#[N:2]

Participants

3

Reactant 2

HCID 887MethanolHCID 20434340HCID 20434340, compound

Product 1

HCID 21285245HCID 21285245, compoundYield 88%

Procedure

43 parts of 2-cyano-3-chloro-N-methylmaleimide are introduced into 100 parts by volume of methanol, the mixture is heated at the boil for fifteen minutes and then cooled, and thereafter the precipitate is filtered off under suction, washed with a small amount of methanol and dried. 37 parts (88% of theory) of 2-cyano-3-methoxy-N-methylmaleimide of melting point 123°-125° C. are obtained. IR (KBr): 2220, 1720, 1640 cm-1.

Workup

  1. temperaturethe mixture is heated at the boil for fifteen minutes
  2. temperaturecooled
  3. filtrationthe precipitate is filtered off under suction
  4. washwashed with a small amount of methanol
  5. customdried

Sources & evidence

ORD record
ord-0d13306bd5b74bcfa9c0d90da4be50f4
Source dataset
uspto-grants-1984_12
Patent number
US04490541

Reaction notes

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