HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → 3-[2-(4-Bromophenyl)thiazol-4-yl]butanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 4-Bromothiobenzamide | HCID 1549289 | — |
| Reactant | 6-Chloro-5-oxohexanenitrile | HCID 10820669 | — |
| Product | 3-[2-(4-Bromophenyl)thiazol-4-yl]butanenitrile | HCID 20504741 | — |
Reaction Steps
A mixture of 4-bromothiobenzamide (2.16 g., 0.01 mole) and 6-chloro-5-oxohexanenitrile (2.28 g., 0.012 mole) is heated at 60° C. in toluene for 12 hours. On cooling and partial evaporation, there is obtained 3-[2-(4-bromophenyl)thiazol-4-yl]butanenitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04298743 |
| Source dataset | uspto-grants-1981_11 |
| ORD ID | ord-3b312a407a584229a6ebfac058c64cf2 |
| Source note | uspto-grants-1981_11 |