HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)phenylhydrazine Hydrochloride → HCID 12813180, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)phenylhydrazine Hydrochloride | HCID 2733310 | — |
| Reactant | 1,2-Dihydro-1-methyl-2-phenyl-4-[3-(trifluoromethyl)phenyl]-3H-pyrazol-3-one | HCID 12813176 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 12813180 | HCID 12813180 | — |
Reaction Steps
A 3.5 gram portion of the atropic ester of Example 1 was reacted with 2.7 grams α,α,α-trifluoro-3-tolylhydrazine hydrochloride in the presence of triethylamine to produce 2.4 grams 1,4-bis-(α,α,α-trifluoro-3-tolyl)-3-pyrazolin-5-one, m.p. 207°-208° C. A 1.8 gram portion of the above pyrazolinone was alkylated with 2 grams methyl iodide to produce 1.25 grams of the desired product, m.p. 110°-111° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04299614 |
| Source dataset | uspto-grants-1981_11 |
| ORD ID | ord-1ab2da669b4f42ae821b849744c70513 |
| Source note | uspto-grants-1981_11 |