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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1155026Generated: November 1, 2026

L-Proline → HCID 54203320, compound

https://huagongshe.com/reaction/1155026

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-ProlineHCID 145742—
ReactantIndole-3-(4'-oxo)butyric acidHCID 730037—
ProductHCID 54203320HCID 54203320—

Reaction Steps

As for Example 1, 4-oxo-4-(3-indolyl)butyric acid (0.1 mole) is coupled to L-proline to give 1-[3-(3-indolylcarbonyl)propionyl]-L-proline. The preceding compound is reacted with bromine in acetic acid and the brominated derivative is reacted with sodium thioacetate in acetonitrile to give the product of the Example as a glass.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04299769
Source datasetuspto-grants-1981_11
ORD IDord-81d9bdbf0f764f1cab961ea788dbbabc
Source noteuspto-grants-1981_11