反应详情

Using the procedure of Example 1, 2,8-bis-(trifluoromethyl)-4-hydroxy-3-quinoline-carboxylic acid chloride and 2-amino-N-methyl-imidazole were reacted to obtain a 33.9% yield of 2,8-bis-(trifluoromethyl)-4-hydroxy-N-(1-methyl-1H-imidazol-2-yl-)-3-quinolinecarboxamide melting at 259° C.

1. customwere reacted