Methane → HCID 86738095, compound

Participants

Reaction Steps

A mixture of 12.3 g (0.054 M) of N-acetyl tryptophan (DL), 4.5 g (0.052 M) morpholine, 75 g absolute ethyl alcohol and 1 g carbon black was refluxed under agitation for 2 hours. It was filtered while hot and concentrated in vacuo to half the volume, after which 200 g of dry acetone was poured in, with agitation. The crystals which were white, were centrifuged and dried, yielding 16 g of morpholine N-acetyl tryptophanate (DL; m.p. 200° C.). The product can be determined with perchloric acid in an acetic medium. The purity was found to be between 99 and 100%.

Provenance & Evidence