反应详情

293.7 g (2.2 mols) of aluminium chloride are introduced in portions to a solution of 377 g (2 mols) of 2-chlorobiphenyl in 160 ml (2 mols) of chloroacetyl chloride and 1,000 ml of methylene chloride. After 18 hours, the reaction mixture is poured onto ice and hydrochloric acid. The organic phase is seperated off, washed, dried over sodium sulphate and concentrated in vacuo by distilling off the solvent. The oil which remains is purified by distillation. 478.7 g (90% of theory) of 4(2-chlorophenyl)phenacyl chloride of melting point 47° C. are obtained.

1. customThe organic phase is seperated off
2. washwashed
3. dry with materialdried over sodium sulphate
4. concentrationconcentrated in vacuo
5. distillationby distilling off the solvent
6. distillationThe oil which remains is purified by distillation