HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 3-Hydroxy-7beta-phenoxyacetylamino-cepham-4alpha-carboxylic acid diphenylmethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 3-Hydroxy-7beta-phenoxyacetylamino-3-cephem-4-carboxylic acid diphenylmethyl ester | HCID 54708251 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Hydroxy-7beta-phenoxyacetylamino-cepham-4alpha-carboxylic acid diphenylmethyl ester | HCID 70570096 | — |
Reaction Steps
In the same manner as that described under (b), 516 mg of 3-hydroxy-7β-phenoxyacetylamino-3-cephem-4-carboxylic acid diphenylmethyl ester (crude product) in 5.1 ml of glacial acetic acid are reduced with 94 mg of sodium borohydride and worked up. The title compound having the properties mentioned under (a) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04301279 |
| Source dataset | uspto-grants-1981_11 |
| ORD ID | ord-19722a8bceae43c0b5825162ba31f3c5 |
| Source note | uspto-grants-1981_11 |