HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 3-Hydroxy-7beta-phenoxyacetylamino-cepham-4alpha-carboxylic acid diphenylmethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 3-Hydroxy-7beta-phenoxyacetylamino-3-cephem-4-carboxylic acid diphenylmethyl ester | HCID 54708251 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Hydroxy-7beta-phenoxyacetylamino-cepham-4alpha-carboxylic acid diphenylmethyl ester | HCID 70570096 | — |
Reaction Steps
In the same manner as that described under (a), 111 g of 3-hydroxy-7β-phenoxyacetylamino-3-cephem-4-carboxylic acid diphenylmethyl ester (crude product) in a mixture of 640 ml of dimethylformamide and 160 ml of glacial acetic acid are reduced with 4.5 g of sodium borohydride and worked up. The title compound having the properties mentioned under (a) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04301279 |
| Source dataset | uspto-grants-1981_11 |
| ORD ID | ord-bdcf75c5a5fb419f802979c238d46a71 |
| Source note | uspto-grants-1981_11 |