反应详情

This compound was prepared in the manner of Example IV, using 8.2 grams (0.045 mole) of 2-ethyl-2-methylmalonyl dichloride, 7.1 grams (0.045 mole) of N-(2-chlorophenylmethyl)hydroxylamine and 16 ml of pyridine in 184 ml of methylene chloride. After purification on a silica gel column, 8.2 grams of 2-[(2-chlorophenyl)methyl]-4-ethyl-4-methylisoxazolidine-3,5-dione were obtained as an oil. The nmr and the ir spectra were consistent with the assigned structure.

1. customThis compound was prepared in the manner of Example IV
2. customAfter purification on a silica gel column