Water → HCID 20561097, compound

HRID 1155514Notes

Reaction equation

HRID 1155514 reaction equation
[CH2:1]([S:3][CH2:4][CH2:5][O:6][C:7]([N:9]([CH3:24])[C:10](=[O:23])[O:11][C:12]1[C:20]2[O:19][C:18]([CH3:22])([CH3:21])[CH2:17][C:16]=2[CH:15]=[CH:14][CH:13]=1)=[O:8])[CH3:2].[OH2:25]>C(O)(=O)C>[CH2:1]([S:3]([CH2:4][CH2:5][O:6][C:7]([N:9]([CH3:24])[C:10](=[O:23])[O:11][C:12]1[C:20]2[O:19][C:18]([CH3:21])([CH3:22])[CH2:17][C:16]=2[CH:15]=[CH:14][CH:13]=1)=[O:8])=[O:25])[CH3:2]

Participants

4

Reactant 2

HCID 962WaterHCID 20561098HCID 20561098, compound

Product 1

HCID 20561097HCID 20561097, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2.7 ml of 40% strength hydrogen superoxide were added dropwise to 10.6 g (0.03 mol) of 2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-(2-ethylthioethoxycarbonyl)-N-methyl-carbamate in 40 ml of glacial acetic acid at 0° C. The next day, the mixture was poured into 300 ml of water and extracted with methylene chloride. The solution was neutralized with sodium bicarbonate. After filtration, the organic phase was worked up as described in Example 1. Yield: 11 g of a colorless oil (98% of theory) of nD20 =1.5320.

Workup

  1. extractionextracted with methylene chloride
  2. filtrationAfter filtration

Sources & evidence

ORD record
ord-24110d397c9845539be117446aae27c4
Source dataset
uspto-grants-1981_11
Patent number
US04302466

Reaction notes

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