Hydrazine hydrate (1:1) → 1-(2-Hydrazino-4-pyridyl)-1-ethylenedioxyethane

Participants

Reaction Conditions

Reaction Steps

A mixture of 11.4 g. (57 mmoles) of 1-(2-chloro-4-pyridyl)-1-ethylenedioxyethane in 50 ml. of 98% hydrazine hydrate was heated to reflux for 15 hours. The mixture was cooled at 0° C. for 2 hours and the resulting precipitate was filtered and dried to give 10.3 g. (92%) of the desired compound. The analytical sample was recrystallized from toluene-cyclohexane.

Provenance & Evidence