3-Methyl-2-buten-1-OL → 3,3-dimethylpent-4-enoic aicd N,N-dimethylamide

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Reaction Steps

147 g of 3-methyl-but-2-en-1-ol are added to 180 g of a mixture of 72.5% by weight of N,N-dimethylacetamide-dimethylacetal and 27.5% by weight of 1-dimethylamino-1-methoxyethylene, and the batch is brought to 144° C. in the course of 80 minutes, whilst at the same time distilling the resulting methanol from the reaction mixture. The batch is then heated for 100 minutes at 144°-154° C. Distillation through a short column gives 205 g (90%) of 3,3-dimethyl-pent-4-enoic acid N,N-dimethylamide (of boiling point 70° C./2.6 mbar), corresponding to a yield of 90% of theory.

Provenance & Evidence