HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 54522879, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Levulinic Acid | HCID 11579 | — |
| Reactant | [4-(Trifluoromethyl)phenyl]hydrazine--hydrogen chloride (1/1) | HCID 24229790 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 54522879 | HCID 54522879 | — |
Reaction Steps
A stirred mixture of 11.6 g. of levulinic acid, 21.3 g. of 4-trifluoromethylphenylhydrazine hydrochloride, 125 ml. of ethanol and 10 ml. of concentrated sulfuric acid is heated under reflux for 24 hours. The reaction mixture is poured onto chopped ice and water. A precipitate forms and is collected by filtration to give ethyl-2-methyl-5-trifluoromethyl-3-indoleacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04302589 |
| Source dataset | uspto-grants-1981_11 |
| ORD ID | ord-e0846d9dbcda444bbabad44fc22d961a |
| Source note | uspto-grants-1981_11 |