HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloronicotinamide → HCID 12862364, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloronicotinamide | HCID 80456 | — |
| Reactant | ethyl 2-amino-5-propylthiophene-3-carboxylate | HCID 3399457 | — |
| Product | HCID 12862364 | HCID 12862364 | 312% |
Reaction Steps
From 4.6 g (0.0029 mol) of 6-chloro-3-pyridinecarboxamide (Aldrich Chemical Company) and 8.6 g (0.040 mol) of 2-amino-5-propyl-3-thiophenecarboxylic acid, ethyl ester, following the procedure of Example 22 there is obtained 2.6 g of 4-oxo-2-propyl-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidine-7-carboxamide; mp 260-264° C. after recrystallization from pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04332947 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-830fbbd0aad24cdcb6b0a5657e52d6bf |
| Source note | uspto-grants-1982_06 |