Dimethylamine → 2-(2-Hydroxy-5-cyanophenyl)-2-methyl N,N-dimethyl-propanoamide

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Reaction Steps

A suspension of 5-cyano-2,3-dihydro-3,3-dimethylbenzofuran-2-one (3.7 g), prepared as in Example 3, in diethyl ether (50 ml) was treated with a solution of dimethylamine in ethanol (8.6 ml of a 20.8% solution) portionwise with stirring at room temperature. The mixture was stirred for two hours, and the product was isolated by filtration, yield 4 g, mp 146°-148° C.

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