HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-Cyano-2,3-dihydro-3,3-dimethylbenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,3-Dihydro-3,3-dimethylbenzofuran-5-carboxylic acid amide | HCID 54089631 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 5-Cyano-2,3-dihydro-3,3-dimethylbenzofuran | HCID 20536190 | — |
Reaction Steps
The product of stage (c) was boiled under reflux in benzene (5 ml) with thionyl chloride for 6 hours. Washing with water, drying over magnesium sulphate and running down gave, after recrystallisation from petroleum ether (bp 60°-80° C.), 0.6 g of title product, mp 70°-72° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04333759 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-675ad276e4664f75b4adb9a81a02dfaf |
| Source note | uspto-grants-1982_06 |