Phenethyl bromide → 4-(4-Nitrophenoxy)-4-phenyl-1-(2-phenylethyl)piperidine

HRID 1156034Notes

Reaction equation

[N+:1]([C:4]1[CH:22]=[CH:21][C:7]([O:8][C:9]2([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:23]1([CH2:29][CH2:30]Br)[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([O:8][C:9]2([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:10][CH2:11][N:12]([CH2:30][CH2:29][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:13][CH2:14]2)=[CH:21][CH:22]=1)([O-:3])=[O:2]

Participants

Reactant 2

HCID 7666Phenethyl bromide

HCID 200299564-(4-Nitrophenoxy)-4-phenylpiperidine

Product 1

HCID 205365734-(4-Nitrophenoxy)-4-phenyl-1-(2-phenylethyl)piperidine

Procedure

from 4-(4-nitrophenoxy)-4-phenylpiperidine and 2-phenylethyl bromide.

Sources & evidence

ORD record: ord-19e76d6b30e448359647914248047f18
Source dataset: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04333942

Reaction notes

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