HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70544774, compound → HCID 86738407, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70544774 | HCID 70544774 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86738407 | HCID 86738407 | 99.4% |
Reaction Steps
A solution of 1.3 g of 16-ethylidene-3-methoxy-18-methyl-1,3,5(10)-estratrien-17-one in 180 ml of ethanol is hydrogenated, after adding 130 mg of 10% palladium charcoal, at room temperature and normal pressure. After absorbing 115 ml of hydrogen the reaction product is filtered off from the catalyst and the filtrate concentrated. Crystallization from methanol yields 1.3 g of 16β-ethyl-3-methoxy-18-methyl-1,3,5(10)-estratrien-17-one, m.p. 101°-102° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04333928 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-5315c6a7344c499db953459c3002437f |
| Source note | uspto-grants-1982_06 |