HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 13251646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2,2,3,3-Tetramethylcyclopropane-1-carbonyl chloride | HCID 11041002 | — |
| Reactant | 4-Phenyl-2,3-dihydro-1H-inden-2-ol | HCID 12942388 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13251646 | HCID 13251646 | 63.2% |
Reaction Steps
In a manner similar to Example 12A, the reaction of 1.09 g (0.007 mole) of 2,2,3,3-tetramethylcyclopropanecarbonyl chloride and 1.5 g (0.007 mole) of (+)-4-phenyl-2-indanol (EE ≥95%) in the presence of 0.7 g (0.009 mole) of pyridine and 20 ml of toluene gave 1.48 g of (+)-4-phenyl-2-indanyl 2,2,3,3-tetramethylcyclopropanecarboxylate, EE≥95%. The nmr spectrum was consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04333950 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-21371540fac44d5599d35129da4a2074 |
| Source note | uspto-grants-1982_06 |