Ethyl bromoacetate → Ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-5-indanyloxy]acetate

HRID 1156187Notes

Reaction equation

HRID 1156187 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][CH:7]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[C:8]2=[O:12])=[CH:4][C:3]=1[OH:20].Br[CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24]>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][CH:7]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[C:8]2=[O:12])=[CH:4][C:3]=1[O:20][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24]

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 130652976,7-Dichloro-5-hydroxy-2-(p-chlorophenyl)-1-indanone

Product 1

HCID 12774097Ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-5-indanyloxy]acetate

Procedure

Reaction of of 6,7-dichloro-5-hydroxy-2-(p-chlorophenyl)-1-indanone with ethyl bromoacetate according to the procedure of Example 1, STEP (a), affords the title compound, m.p. 159.5°-160° (crystallized from ethanol-acetone).

Workup

  1. customaffords
  2. customthe title compound, m.p. 159.5°-160° (crystallized from ethanol-acetone)

Sources & evidence

ORD record
ord-a9990990ce474d7496b0dc59e992fedf
Source dataset
uspto-grants-1982_06
Patent number
US04334088

Reaction notes

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