3-Bromo-1-(trimethylsilyl)-1-propyne → HCID 13065299, compound

HRID 1156192Notes

Reaction equation

HRID 1156192 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][CH:7]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=3)[C:8]2=[O:12])=[CH:4][C:3]=1[O:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23].Br[CH2:28][C:29]#[C:30][Si:31]([CH3:34])([CH3:33])[CH3:32]>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][C:7]([C:13]3[CH:14]=[CH:15][C:16]([F:19])=[CH:17][CH:18]=3)([CH2:28][C:29]#[C:30][Si:31]([CH3:34])([CH3:33])[CH3:32])[C:8]2=[O:12])=[CH:4][C:3]=1[O:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23]

Participants

3

Reactant 2

HCID 6425893-Bromo-1-(trimethylsilyl)-1-propyneHCID 12774098HCID 12774098, compound

Product 1

HCID 13065299HCID 13065299, compound

Procedure

Reaction of ethyl [6,7-dichloro-1-oxo-2-(p-fluorophenyl)-5-indanyloxy]acetate with 1-bromo-3-(trimethylsilyl)-2-propyne according to the procedure of Example 1, STEP (b), affords the title compound as an oil.

Sources & evidence

ORD record
ord-b9912ea322d548f2be044d86b945e2e0
Source dataset
uspto-grants-1982_06
Patent number
US04334088

Reaction notes

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