Acetamide, 2-chloro-N-(2,6-dinitrophenyl)- → HCID 20535499, compound

Participants

Reaction Steps

2.5 g. of 2',6'dinitro-2-chloroacetanilide, 3.0 ml. of chloromethyl n-propyl ether, 150 ml of methylene chloride and 1.1 gr. of phase transfer catalyst were charged to a round-bottom flask fitted with a mechanical stirrer. To the mixture was added 100 ml. of saturated NA2CO3 in one portion. The resulting mixture was stirred for three-quarter hour at which time GLC showed no starting material indicating the reaction was complete. The product, 2-chloro-2',6'-dinitro-N-(n-propoxymethyl)acetanilide was obtained as a yellow oil, (3.1 g., yield 93%)

Provenance & Evidence